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Creamy Cajun chicken Alfredo pasta served with Parmesan and fresh parsley.

Creamy Cajun Chicken Alfredo Pasta – Restaurant Style Dinner at Home


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  • Author: Raelynn
  • Total Time: 35 minutes
  • Yield: 4 servings 1x

Description

Creamy Cajun Chicken Alfredo Pasta is a rich restaurant-style dinner made with Cajun-spiced chicken, tender pasta, and a velvety homemade Alfredo sauce with garlic, cream, and Parmesan cheese.


Ingredients

Scale
  • 2 large boneless skinless chicken breasts
  • 1 tablespoon Cajun seasoning
  • 1/2 teaspoon paprika
  • 1/2 teaspoon garlic powder
  • 1/2 teaspoon onion powder
  • 1/2 teaspoon black pepper
  • 1/2 teaspoon salt
  • 2 tablespoons olive oil
  • 12 ounces fettuccine pasta
  • 4 quarts water
  • 1 tablespoon salt
  • 3 tablespoons butter
  • 4 cloves garlic, minced
  • 2 cups heavy cream
  • 1 cup freshly grated Parmesan cheese
  • 1/2 teaspoon Cajun seasoning
  • 1/4 teaspoon black pepper
  • 1/4 teaspoon salt
  • 1/2 teaspoon smoked paprika
  • 1/2 cup reserved pasta water
  • Fresh parsley, chopped (optional garnish)
  • Extra Parmesan cheese (optional garnish)
  • Crushed red pepper flakes (optional garnish)
  • Lemon zest (optional garnish)

Instructions

  1. Pat the chicken breasts dry with paper towels. Season both sides with Cajun seasoning, paprika, garlic powder, onion powder, salt, and black pepper.
  2. Heat olive oil in a large skillet over medium-high heat. Cook the chicken for 5–7 minutes per side until golden and fully cooked. Internal temperature should reach 165°F (75°C). Remove and rest.
  3. Bring a large pot of water to a boil. Add salt and cook the fettuccine according to package directions until al dente. Reserve 1 cup pasta water, then drain.
  4. Slice the rested chicken into thin strips.
  5. In the same skillet melt butter over medium heat. Add minced garlic and cook about 30 seconds until fragrant.
  6. Pour in the heavy cream and gently simmer for 3–4 minutes, scraping up browned bits from the pan.
  7. Stir in the Parmesan cheese until melted and smooth.
  8. Season the sauce with Cajun seasoning, smoked paprika, salt, and black pepper.
  9. Add a little reserved pasta water if needed to adjust the sauce consistency.
  10. Add the cooked pasta to the skillet and toss until fully coated in Alfredo sauce.
  11. Top with sliced Cajun chicken and gently mix.
  12. Garnish with parsley, extra Parmesan cheese, and optional red pepper flakes before serving.

Notes

  • Freshly grated Parmesan melts better and creates a smoother Alfredo sauce.
  • Half-and-half can replace part of the heavy cream for a lighter version.
  • Chicken thighs can be used instead of chicken breasts for extra juiciness.
  • Add vegetables such as spinach, mushrooms, or roasted bell peppers for variety.
  • Store leftovers in the refrigerator up to 3 days and reheat with a splash of milk or cream.
  • Prep Time: 15 minutes
  • Cook Time: 20 minutes
  • Category: Dinner
  • Method: Stovetop
  • Cuisine: Italian-American

Nutrition

  • Serving Size: 1 serving
  • Calories: 620
  • Sugar: 3g
  • Sodium: 720mg
  • Fat: 30g
  • Saturated Fat: 15g
  • Unsaturated Fat: 12g
  • Trans Fat: 0g
  • Carbohydrates: 48g
  • Fiber: 2g
  • Protein: 38g
  • Cholesterol: 120mg