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Creamy Cajun chicken pasta with sausage served with Parmesan and parsley garnish.

Cajun Chicken Pasta with Sausage – Creamy Southern Pasta Recipe


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  • Author: Raelynn
  • Total Time: 35 minutes
  • Yield: 4 servings 1x

Description

Cajun Chicken Pasta with Sausage is a creamy Southern-inspired pasta recipe made with Cajun-seasoned chicken, smoky sausage, tender pasta, and a rich Parmesan cream sauce.


Ingredients

Scale
  • 2 boneless skinless chicken breasts
  • 1 tablespoon Cajun seasoning
  • 1/2 teaspoon paprika
  • 1/2 teaspoon garlic powder
  • 1/2 teaspoon onion powder
  • 1/2 teaspoon black pepper
  • 1/2 teaspoon salt
  • 2 tablespoons olive oil
  • 8 ounces smoked sausage (Andouille or smoked beef sausage)
  • 1 tablespoon olive oil
  • 12 ounces penne pasta
  • 4 quarts water
  • 1 tablespoon salt
  • 3 tablespoons butter
  • 4 cloves garlic, minced
  • 1 small onion, finely diced
  • 1 red bell pepper, sliced
  • 1 1/2 cups heavy cream
  • 1 cup grated Parmesan cheese
  • 1 teaspoon Cajun seasoning
  • 1/2 teaspoon smoked paprika
  • 1/4 teaspoon black pepper
  • 1/4 teaspoon salt
  • 1/2 cup reserved pasta water
  • Fresh parsley, chopped (optional garnish)
  • Extra grated Parmesan (optional garnish)
  • Crushed red pepper flakes (optional garnish)
  • Lemon zest (optional garnish)

Instructions

  1. Pat the chicken breasts dry with paper towels and season both sides with Cajun seasoning, paprika, garlic powder, onion powder, salt, and black pepper.
  2. Heat 2 tablespoons olive oil in a large skillet over medium-high heat and cook the chicken for 5–7 minutes per side until golden and fully cooked. Remove and let rest.
  3. Slice the smoked sausage into thin rounds.
  4. Add olive oil to the same skillet and cook the sausage until browned and slightly crisp. Remove and set aside if needed.
  5. Bring a large pot of salted water to a boil and cook the pasta according to package directions until al dente. Reserve 1 cup pasta water before draining.
  6. Slice the rested chicken into thin strips.
  7. In the same skillet melt butter and sauté garlic, diced onion, and red bell pepper for 3–4 minutes until softened.
  8. Pour in the heavy cream and simmer gently while scraping up the flavorful browned bits from the pan.
  9. Stir in the grated Parmesan cheese until melted and smooth.
  10. Season the sauce with Cajun seasoning, smoked paprika, salt, and black pepper.
  11. Add a little reserved pasta water if needed to adjust the sauce consistency.
  12. Add cooked pasta to the skillet and toss to coat with the creamy Cajun sauce.
  13. Return the sliced chicken and cooked sausage to the pan and toss everything together.
  14. Garnish with parsley, Parmesan, and optional red pepper flakes before serving.

Notes

  • Freshly grated Parmesan melts better and creates a smoother Alfredo-style sauce.
  • Andouille sausage adds authentic Cajun flavor, but smoked beef sausage also works well.
  • You can add mushrooms, spinach, or zucchini for extra vegetables.
  • For extra spice add cayenne pepper or additional Cajun seasoning.
  • Leftovers keep in the refrigerator for up to 3 days and reheat well with a splash of milk or cream.
  • Prep Time: 15 minutes
  • Cook Time: 20 minutes
  • Category: Dinner
  • Method: Stovetop
  • Cuisine: Southern / Cajun Inspired

Nutrition

  • Serving Size: 1 serving
  • Calories: 680
  • Sugar: 4g
  • Sodium: 880mg
  • Fat: 34g
  • Saturated Fat: 16g
  • Unsaturated Fat: 15g
  • Trans Fat: 0g
  • Carbohydrates: 50g
  • Fiber: 3g
  • Protein: 40g
  • Cholesterol: 125mg